Table 2.
Estimates of association parameters
| Markers
|
ε | σε | L | σL | M | σM | Residual χ2
|
|||
|---|---|---|---|---|---|---|---|---|---|---|
| First | Second | ρ | Δ | df | ||||||
| Haplotypes with major disease locus | ||||||||||
| S | S | .0019 | .0004 | .1505 | .0561 | .7663 | .0319 | 1316.78 | 2707.38 | 352 |
| D | S | .0032 | .0040 | .1715 | .0961 | .6378 | .2039 | 482.35 | — | 48 |
| D | N | .0028 | .0008 | .2830 | .0308 | 1.0000 | .1016 | 570.41 | — | 67 |
| All | All | .0028 | .0004 | .2520 | .0207 | .7636 | .0352 | 2547.10 | — | 473 |
| Random haplotypes | ||||||||||
| S | S | .0038 | .0014 | .1810 | .0621 | .6031 | .0356 | 3610.54 | 5991.64 | 549 |
| Total | .0032 | .0005 | .2432 | .0204 | .6340 | .0248 | 6434.83 | — | 1025 | |
S, SNP; N, non-SNP; D, major disease locus.