Table 1.

Age, body weight, baseline ventilation and oxygen consumption of wild-type control and 5-HTT knockout mice

	Age (days)	Body weight (g)	f (min−1)	VT (ml g−1)	(ml min−1 g−1)	(ml min−1 g−1)	Tbody (°C)
Male WT (n= 5)	163 ± 12	31 ± 2	205 ± 5	0.012 ± 0.001	2.31 ± 0.09	0.060 ± 0.002	36.6 ± 0.2	39 ± 2
Male KO (n= 7)	165 ± 7	29 ± 1	254 ± 9	0.011 ± 0.0002	2.90 ± 0.11	0.080 ± 0.002	37.0 ± 0.2	37 ± 2
	n.s.	n.s.	*	n.s.	*	+	n.s.	n.s.
Female WT (n= 6)	181 ± 10	24 ± 1	192 ± 9	0.015 ± 0.001	2.83 ± 0.21	0.078 ± 0.003	36.5 ± 0.2	37 ± 2
Female KO (n= 6)	168 ± 8	25 ± 1	235 ± 6	0.014 ± 0.001	3.35 ± 0.18	0.093 ± 0.005	36.8 ± 0.2	36 ± 2
	n.s.	n.s.	*	n.s.	n.s.	+	n.s.	n.s.

Values are means ±s.e.m.

^*P < 0.01; ⁺P < 0.05; t test applied within each sex. f, breathing frequency; V_T, tidal volume; , ventilation; , oxygen consumption; T_body, body temperature; , ventilatory equivalent.