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. 2008 Mar 13;586(Pt 9):2357–2370. doi: 10.1113/jphysiol.2007.150532

Figure 6. Attenuation of AMPA-mediated currents by SYM 2206 (10 or 100 μM) in XII motoneurons.

Figure 6

A, membrane current responses to local application of AMPA in control and SYM 2206 (10 μm). Pooled data showing a partial, but insignificant, reduction of AMPA-mediated currents in the presence of SYM 2206 (10 μm) (n = 3). Square-wave steps are voltage pulses delivered to test membrane resistance. B, membrane current response from a XII motoneuron showing a reduction in the AMPA-mediated current by SYM 2206 (100 μm). Pooled data showing a significant reduction of AMPA currents in SYM 2206 (Student's paired t test; n = 8). Ψ indicates current response to voltage ramp. Asterisks indicate significance, ***P < 0.001.