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D4 receptor agonist, PD 168,077, inhibits depolarization-evoked increase in [Ca2+]i in chicken photoreceptor cells. A. The inhibitory effect of PD 168,077 on [Ca2+]i was concentration-dependent (0.025–1.0 μM), with significant inhibition at concentrations of 0.1 μM and above (** p<0.01). B. The inhibitory effect of 0.1 μM PD 168,077 (** p<0.01 vs. control; n=20) was blocked by 1.0 μM L 745,870 (††p<0.01 vs. PD 168,077 n=9).
