Table 2.
Top 20 KEGG pathways enriched in advanced stage pancreatic carcinoma microarray data
| KEGG IDa | Pathway | P value | Gene(s)a |
|---|---|---|---|
| hsa03010 | Ribosome | 0 | RPS5, RPS26 |
| hsa04010 | MAPK signaling pathway | 0 | FOSB, TAOK1, EGFR, PRKAB2 |
| hsa04360 | Axon Guidance | 0 | - |
| hsa04510 | Focal adhesion | 0 | EGF, PTEN, THBS1, VWF, EGFR |
| hsa04514 | Cell adhesion molecules (CAMs) | 0 | HLA-DOA, HLA-DQB1 |
| hsa04520 | Adherens junction | 0 | WASL, EGFR |
| hsa04530 | Tight junction | 0 | PPP2R1B |
| hsa04612 | Antigen processing and presentation | 0 | HLA-DOA, HLA-DQB 1 |
| hsa04640 | Hematopoietic cell lineage | 0 | HLA-DRB4, HLA-DRB5 |
| hsa04660 | T cell receptor signaling pathway | 0 | FOSB |
| hsa04662 | B cell receptor signaling pathway | 0 | FOSB |
| hsa04664 | Fc epsilon RI signaling pathway | 0 | - |
| hsa04810 | Regulation of actin cytoskeleton | 0 | EGF, WASL, EGFR |
| gamma-Hexachlorocyclohexane | - | ||
| hsa00361 | degradation | 0.001 | |
| hsa00460 | Cyanoamino acid metabolism | 0.001 | - |
| hsa00561 | Glycerophospholipid metabolism | 0.001 | PPAPDC1B |
| hsa04120 | Ubiquitin mediated proteolysis | 0.001 | UBE2D4 |
| hsa04310 | Wnt signaling pathway | 0.001 | THEM4(CTBP1), PPP2R1B |
| hsa04670 | Leukocyte transendothelial migration | 0.001 | - |
| hsa04910 | Insulin signaling pathway | 0.001 | PRKAB2, SOCS3 |
a
Pathway identifiers as listed on the KEGG Pathway Finder at T1D Base (http://www.t1dbase.org). The genes shown in the right-most column are representative genes that were used for KEGG pathway analysis.