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. 2008 Jan 1;1(4):343–351.

Table 1.

Summary of FISH analysis of 59 cases of sporadic pancreatic cancer

Average # of signals per nucleus

case # # of nuclei scored EMSY C11 EMSY/C11 ratio
1 133 1.86 1.56 1.19
2 128 1.69 1.67 1.01
3 123 1.51 1.49 1.01
4 115 1.46 1.42 1.03
5 135 2.55 2.02 1.26
6 129 2.58 2.35 1.1
7 79 1.72 1.78 0.97
8 122 2.02 1.91 1.06
9 103 1.75 1.63 1.07
10 118 1.52 1.47 1.03
11 122 1.83 1.73 1.06
12 169 3.93 2.39 1.64
13 126 1.57 1.45 1.08
14 109 2.99 1.87 1.6
15 121 2.11 1.75 1.21
16 86 1.76 1.55 1.14
17 152 3.31 1.42 2.33
18 131 1.81 1.54 1.18
19 135 1.44 1.37 1.05
20 104 1.55 1.5 1.03
21 45 1.66 1.44 1.15
22 153 2.2 1.39 1.58
23 126 1.54 1.58 0.97
24 73 2.47 2.44 1.01
25 135 1.62 1.51 1.07
26 138 2.47 1.49 1.66
27 67 1.49 1.43 1.04
28 99 1.59 1.58 1.01
29 128 1.94 1.68 1.15
30 111 1.62 1.48 1.09
31 123 1.57 1.49 1.05
32 110 2 1.66 1.2
33 171 2.61 1.49 1.75
34 62 2.69 2.36 1.14
35 117 1.83 1.69 1.08
36 54 2.98 2.11 1.41
37 127 2.02 1.91 1.06
38 134 2.19 2.06 1.06
39 140 3.42 2.26 1.51
40 145 4.01 2.99 1.34
41 137 1.47 1.53 0.96
42 160 1.67 1.54 1.08
43 198 2.96 2.27 1.3
44 141 2.27 1.91 1.19
45 123 1.56 1.53 1.02
46 158 2.16 1.95 1.11
47 84 1.49 1.57 0.95
48 146 1.64 1.62 1.01
49 166 1.8 1.53 1.18
50 119 1.88 1.67 1.13
51 72 2.27 1.99 1.14
52 164 2.68 1.74 1.54
53 132 1.99 1.65 1.21
54 102 1.59 1.55 1.03
55 74 1.54 1.47 1.05
56 170 1.63 1.67 0.98
57 168 1.58 1.56 1.01
58 166 1.93 1.71 1.13
59 191 1.58 1.54 1.03

37.3% had an increased copy number (>2.0 signals on average per nucleus) 13.6% had EMSY amplification (ratio >1.5)

Inline graphic EMSY amplification

Inline graphic Increased EMSY copy number