Fig. 2.

Presence or absence of complement component genes in various animal groups. All complement components and related genes of human, as a representative of Mammalia, are shown, and the presence of the orthologous genes reported from the other animal groups are indicated by the reference numbers. Plus and minus indicate the presence and absence, respectively, of the orthologous genes in the assembled genome sequences of at least one representative species of each group. Genes located outside of the complement gene clusters in the phylogenetic tree, showing an uncertain orthologous relationship with complement genes, are indicated in red. Literatures cited here are: 1 Mavroidis et al. 1995; 2 Fritzinger et al. 1992; 3 Kaufman et al. 1999; 4 Kjalke et al. 1993; 5 Laursen et al. 1998; 6 Lynch et al. 2005; 7 Oshiumi et al. 2005; 8 Mahon et al. 1999; 9 Grossberger et al. 1989; 10 Mo et al. 1996; 11 Kato et al. 1995; 12 Kato et al. 1994; 13 Endo et al. 1998 and Kakinuma et al. 2003; 14 Endo et al. 1998; 15 Kunnath-Muglia et al. 1993; 16 Boshra et al. 2005; 17 Abelseth et al. 2003; 18 Samonte et al. 2002; 19 Zarkadis et al. 2001; 20 Nakao et al. 2000; 21 Kuroda et al. 2000; 22 Sato et al. 1999; 23 Sunyer et al. 1997b; 24 Sunyer et al. 1997a; 25 Sunyer et al. 1996; 26 Lambris et al. 1993; 27 Boshra et al. 2004a; 28 Wang and Secombes 2003; 29 Sambrook et al. 2003; 30 Kato et al. 2003; 31 Franchini et al. 2001; 32 Nakao et al. 2002; 33 Sunyer et al. 1998; 34 Nakao et al. 1998; 35 Gongora et al. 1998; 36 Seeger et al. 1996; 37 Kuroda et al. 1996; 38 Yano and Nakao 1994; 39 Vitved et al. 2000; 40 Nakao et al. 2001; 41 Chondrou et al. 2006; 42 Zarkadis et al. 2005; 43 Papanastasiou and Zarkadis 2005; 44 Uemura et al. 1996; 45 Katagiri et al. 1999; 46 Kazantzi et al. 2003; 47 Yeo et al. 1997; 48 Tomlinson et al. 1993; 49 Nakao et al. 2003a; 50 Kemper et al. 1998; 51 Boshra et al. 2005; 52 Boshra et al. 2004b; 53 Fujiki et al. 2003; 54 Dodds et al. 1998; 55 Terado et al. 2003; 56 Smith 1998; 57 Terado et al. 2002; 58 Ishiguro et al. 1992; 59 Nonaka et al. 1984 and Nonaka and Takahashi 1992; 60 Nonaka et al. 1994; 61 Matsushita et al. 2004; 62 Takahashi et al. 2006; 63 Song et al. 2005; 64 Kimura et al. 2004; 65 dos Remedios et al. 1999; 66 Suzuki et al. 2002; 67 Endo et al. 2003; 68 Raftos et al. 2002; 69 Marino et al. 2002; 70 Nonaka et al. 1999; 71 Yoshizaki et al. 2005; 72 Azumi et al. 2003; 73 Dehal et al. 2002; 74 Kenjo et al. 2001; 75 Sekine et al. 2001; 76 Ji et al. 1997; 77 Miyazawa and Nonaka 2004; 78 Miyazawa et al. 2001; 79 Al-Sharif et al. 1998; 80 Smith et al. 1998; 81 Zhu et al. 2005; 82 Adams et al. 2000; 83 The C. elegans Sequencing Consortium 1998; 84 Dishaw et al. 2005; *1 H. Nagumo et al., unpublished data; and *2 A. Kimura and M. Nonaka, unpublished data