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. 2008 Apr 4;38(4):372–389. doi: 10.1007/s10519-008-9201-8

Table 7.

Number of sib pairs required to detect spurious (H1:B = W vs. H0: B≠W) and genuine (H1:B≠W = 0 vs. H0: B≠W≠0) G × E interaction effects in eight different conditions for power of .80 with α = .05a

Dichotomous environment Continuous environment
B = W B≠W = 0 B = W B≠W = 0
Design(i) 4,745 274 2,543 184
Design(i = c) 4,129 192 3,277 126
Design(i,e) 3,832 274 4,000 184
Design(i,a) 3,470 274 2,071 184
Design(i,a,d) 3,658 274 2,146 184
Design(i,a,e) 2,914 274 3,045 184
Design(−i,a) 6,922 274 3,235 184
Design(−i,a,e) 5,318 274 5,563 184

B = W, test for presence of population stratification; B≠W = 0, test for significance of within-family interaction effect only

aAll tests assume two degrees of freedom