The probability, p, of protein A as a function of the total fractional nativeness, q, and the fractional nativeness of different tertiary contacts. The top row of panels corresponds to tertiary contacts between Helices 2 and 3, qH2-H3, in three separate environments: bulk; tethered at the N-terminus; and tethered at the C-terminus. The bottom row corresponds to tertiary contacts between Helices 1 and 3, qH1-H3, in the same environments. The temperature in each case is equal to the melting temperature of the peptide in the bulk.