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The dynamic activation of NF-κB in macrophages compared with results of prior studies using fibroblasts. Nuclear NF-κB was assayed by EMSA at the indicated times after persistent stimulation with 1 μg/ml LPS in macrophages in this study (□, n = 8, values reported as average ± 95% confidence interval), 0.5 μg/ml LPS in fibroblasts, demonstrated by Covert et al. (27) (○); and 0.1 μg/ml LPS in fibroblasts, demonstrated by Werner et al. (35) (×).
