Table 2. All cause mortality in BRCA2 vs BRCA1 patients with prostate cancer.
|
Univariate
|
Age-adjusted
|
|||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| BRCA2 vs BRCA1 All subjects | 1.64 (1.17–2.30) | 0.005 | 1.71 (1.22–2.41) | 0.002 |
| BRCA2 vs BRCA1 Known carriers | 2.41 (1.28–4.52) | 0.006 | 2.48 (1.31–4.70) | 0.005 |
Hazard ratio represents mortality experience of patients with BRCA2 mutations compared to those with BRCA1 mutations, calculated using Cox proportional hazards model.