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. 2008 Jul 1;99(2):239–244. doi: 10.1038/sj.bjc.6604455

Table 6. Cumulative risk (CR), probabilities of cytological and histological false-positive diagnosis and of true positive per 10 000, ratio between true-positive and false-positive, ratio between CR and false-positive, by screening episodes, for different combination of cytological and histological specificities.

  CR (per 10 000)
  True positive (per 10 000)
True positive/false positive
Positive/false positive
No. of screening episodes 25–49 (years) 50–64 (years) False positive (per 10 000) 25–49 (years) 50–64 (years) 25–49 (years) 50–64 (years) 25–49 (years) 50–64 (years)
Cytological specificity: 0.97, histological specificity: 0.94 or cytological specificity: 0.94, histological specificity: 0.97
 1 206 36 18.00 188.00 18.00 10.44 1 11.44 2
 2 246 38 17.97 228.03 20.03 12.69 1.11 13.69 2.11
 3 274 36 17.94 256.06 18.06 14.28 1.01 15.28 2.01
 4 305 23 17.90 287.10 5.10 16.04 0.28 17.04 1.28
 5 206 23 17.87 188.13 5.13 10.53 0.29 11.53 1.29
                   
Cytological specificity: 0.96, histological specificity: 0.95 or cytological specificity: 0.95, histological specificity: 0.96
 1 206 36 20.00 186.00 16.00 9.30 0.80 10.30 1.80
 2 246 38 19.96 226.04 18.04 11.32 0.90 12.32 1.90
 3 274 36 19.92 254.08 16.08 12.75 0.81 13.75 1.81
 4 305 23 19.88 285.12 3.12 14.34 0.16 15.34 1.16
 5 206 23 19.84 186.16 3.16 9.38 0.16 10.38 1.16