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. 2008 Jul 15;99(2):341–349. doi: 10.1038/sj.bjc.6604471

Table 3. Relationship between proteins and clinicopathological characteristics.

  HER2
EGFR
pEGFR
pAKT
pERK
PTEN
Variable Neg Pos P Neg Pos P Neg Pos P Neg Pos P Neg Pos P Neg Pos P
Age                                    
 <58 years 110/113 3/113 0.14 106/112 6/112 0.44 99/113 14/113 0.84 104/114 10/114 1.00 69/108 39/108 0.89 38/111 73/111 0.31
 >58 years 108/117 9/117   106/116 10/116   102/115 13/115   105/114 9/114   71/114 43/114   31/113 82/113  
                                     
Stage                                    
 Early 59/62 3/62 1.00* 56/61 5/61 0.77* 51/60 9/60 0.49 60/91 1/61 0.029 38/59 21/59 0.88 27/60 33/60 0.006
 Late 157/166 9/166   154/165 11/165   148/166 18/166   147/165 18/165   101/161 60/161   41/162 121/162  
                                     
Histology                                    
 Serous 123/128 5/128 0.38 123/127 4/127 0.017 111/127 16/127 0.84 115//126 11/126 1.00 77/123 46/123 0.89 31/124 93/124 0.042
 Other 95/102 7/102   89/101 12/101   90/101 11/101   94/102 8/102   63/99 36/99   38/100 62/100  
                                     
Grade                                    
 I/II 84/89 5/89 1.00* 82/87 5/87 0.78 75/88 13/88 0.18 85/89 4/89 0.19 49/85 36/85 0.24 32/87 55/87 0.17
 III/undiff 112/118 6/118   109/118 9/118   107/117 10/117   104/116 12/116   76/114 38/114   31/114 83/114  
                                     
Res. tumour                                    
 <2 cm 105/109 4/109 0.54 100/107 7/107 1.00 95/107 12/107 0.84 102/108 6/108 0.31 70/102 32/102 0.15 34/104 70/104 0.55
 ⩾ 2 cm 102/109 7/109   101/109 8/109   95/109 14/109   97/108 11/108   63/108 45/108   31/108 77/108  

Neg=negative; Pos=positive; Res. tumour=residual tumour after primary surgery; undiff=undifferentiated.

P-values are derived from the χ2-test or Fischer's exact test, where appropriate (*signifies the use of the Fischer's exact test).