Table 4. Results of univariate survival analysis.

	Univariate Cox regression analysis
	Hazard ratio	95% confidence interval	P-value
Progression-free survival
EGFR positive	0.55	0.26–1.17	0.12
HER-2/neu positive	0.98	0.46–2.10	0.96
pEGFR positive	0.62	0.35–1.06	0.09
pAKT positive	0.88	0.46–1.67	0.69
pERK positive	1.09	0.77–1.54	0.64
PTEN negative	0.48	0.32–0.72	<0.001
Overall survival
EGFR positive	0.84	0.43–1.65	0.43
HER-2/neu positive	1.02	0.48–2.20	0.94
pEGFR positive	0.64	0.36–1.39	0.13
pAKT positive	1.05	0.58–1.91	0.86
pERK positive	1.04	0.73–1.48	0.84
PTEN negative	0.66	0.44–0.097	0.037

Bold signifies P<0.05.