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. Author manuscript; available in PMC: 2009 Jul 1.
Published in final edited form as: Neurobiol Dis. 2008 Apr 25;31(1):127–132. doi: 10.1016/j.nbd.2008.04.002

Fig.5. Rescue of protrusion morphology in Fmr1 KO primary hippocampal neurons.

Fig.5

Fmr1 KO and wild type neurons were treated for four hours with 200 μm MPEP or 300 μm fenobam. The total amount of protrusions (A) and the amount of mature spines (B) were unaffected by mGluR5 antagonist treatment. The Fmr1 KO phenotype showing an increased number of filopodia was completely rescued by both mGluR5 antagonists (C). Averages of 3 independent experiments, compared with Student's T tests (*=p<0,05, **=p<0,01).