Fig. 5.

Model of S2 cell cytoskeletal fluctuations. Characteristic events and their microscopic interpretations are shown. (a and b) Multiple motors of different polarity operating on different vesicles and multiple microtubules lead to single microtubules buckling away from bundles or bundles globally deforming on the substrate (Figs. 2 a and b and 3b). (c) Cargos carrying multiple motors dynamically cross-link multiple microtubules (hubs) and induce lateral and longitudinal fluctuating forces (Figs. 3a and 4). (d) Multiple vesicles bind statically to a single microtubule and experience passive hitchhiking along the longitudinally fluctuating microtubule (Figs. 1b and 3c).