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. 2008 Aug 6;3(8):e2865. doi: 10.1371/journal.pone.0002865

Figure 3. Effect of aging and calorie restriction on nucleic acid oxidation in gastrocnemius liver weights and non-heme iron content.

Figure 3

A) Total RNA oxidative damage in the gastrocnemius muscles increased with age in AL rats, which did not change over time in CR rats. B) Total DNA oxidative damage in the gastrocnemius muscle increased markedly after 29 months of age in both AL and CR rats. Values are means±SEM (n = 6). a,b,cDifferent letters indicate values are significantly different (p<0.05 by Tukey's Multiple Comparison Test).