Table 3.

Comparison of outcome between daily interruption of sedation and sedation algorithm

	Daily interruption of sedation n = 36		Sedation algorithm n = 38		P value
	Median	95% CI	Median	95% CI
Total duration of mechanical ventilation, days	6.7	4.1, 10.4	3.9	2.9, 4.9	0.0003
Intensive care unit length of stay, days	15	9.1, 21.2	8	6.5, 8.7	< 0.0001
Hospital length of stay, days	23	14.8, 28.7	12	11.3, 16.0	0.01
	Median	IQR	Median	IQR
28-day ventilator-free survival	16.1	0.00, 21.77	23.1	19.16, 25.06	0.004
Midazolam equivalents, mg/kg-day	0.2	0.01, 1.48	0.4	0.01, 1.32	0.70
Fentanyl equivalents, μg/kg-day	0.5	0.09, 2.43	1.2	0.12, 2.44	0.36
Propofol, μg/kg-day	0	0.0, 5817.0	0	0.0, 6589.0	0.39

CI, confidence interval; IQR, interquartile range.