Figure 6.

Heparan sulfate release in coronary venous effluent. (a) Absolute release of heparan sulfate in hearts subjected to 15 minutes of ischemia followed by 20 minutes of reperfusion. (b) Cumulative release of heparan sulfate in hearts subjected to 15 minutes of ischemia followed by 20 minutes of reperfusion (15' + 20') and in hearts subjected to 20 minutes of ischemia followed by 40 minutes of reperfusion (20' + 40'). Hearts were reperfused in the absence (Control group) and presence (NO group) of 4 μM nitric oxide. Values are presented as mean ± standard error of the mean. ^#P < 0.05, intergroup difference versus the Control group. AUC, area under the curve; B, baseline; w.w., wet weight.