. 2008 Jun 30;12(3):162. doi: 10.1186/cc6924

Table 1.

Evolution of the sepsis guidelines

	Organizations involved	Number of participants	Process	Publication
First	1 (ISF)	9^a	EBM A to E	Intensive Care Medicine supplement, 2001
Second	3 (ISF, ESICM, SCCM)^b	24	EBM A to E	Critical Care Medicine and Intensive Care Medicine, 2004
Third	16	55	GRADE	Critical Care Medicine and Intensive Care Medicine, 2008

EBM, evidence-based medicine; ESICM, European Society of Intensive Care Medicine; GRADE, Grading of Recommendations, Assessment, Development, and Evaluation; ISF, International Sepsis Forum; SCCM, Society of Critical Care Medicine. ^aActually there were more participants since there were fellows or junior faculty involved. ^bA number of other societies also participated.