Table 1.
Proteins identified by biopanning from a breast cancer cDNA T7 phage library
Protein | Full name; functions | Score (bits), Ea value (alignment) |
KLF17 | Kruppel-like factor 17; new member of the Sp/KLF family of transcription factors in breast and prostate cancer | 553, 1e-121 (100%) |
COL6A1 | Collagen, type VI, alpha 1; breast cancer and prostate cancer prognosis | 626, 1e-143 (100%) |
GRWD1 | glutamate-rich WD repeat containing 1; overexpression in lung cancer, gastric cancer, and melanoma | 545, 1e-152 (100%) |
ASB-9 | Ankyrin repeat and SOCS box protein 9; overexpression in breast cancer and prostate cancer | 608, 1e-171 (100%) |
SERAC1 | Serine active site containing 1; unknown function | 460, 3e-127 (100%) |
RELT | Receptor expressed in lymphoid tissues; stimulating T-cell proliferation in the presence of CD3 signaling | 422, 1e-115 (100%) |
aThe Expect value (E) is a parameter that describes the number of hits one can "expect" to see by chance when searching a database of a particular size.