Table 3.
Association of CD44/CD24 phenotypes with breast cancer subgroups.
| Phenotype | All tumors (n = 232) | SR+HER2- (n = 150) | SR+HER2+ (n = 14) | SR-HER2+ (n = 24) | SR-HER2- | P valuea | |
| Basal-like (n = 30) | Nonbasal (n = 14) | ||||||
| CD44 | 0.001 | ||||||
| Positive (> 0%) | 75 (32) | 47 (31) | 2 (14) | 4 (17) | 19 (63) | 3 (21) | |
| Negative | 157 (68) | 103 (69) | 12 (86) | 20 (83) | 11 (37) | 11 (78) | |
| CD24 | 0.035 | ||||||
| Positive (> 0%) | 108 (47) | 65 (43) | 8 (57) | 18 (75) | 12 (40) | 5 (36) | |
| Negative | 124 (53) | 85 (57) | 6 (43) | 6 (25) | 18 (60) | 9 (64) | |
| CD44+/CD24- | < 0.001 | ||||||
| Positive (> 0%) | 73 (31) | 47 (31) | 2 (14) | 2 (8) | 19 (63) | 3 (21) | |
| Negative | 159 (69) | 103 (69) | 12 (86) | 22 (92) | 11 (37) | 11 (79) | |
| CD44-/CD24+ | 0.027 | ||||||
| Positive (> 0%) | 106 (46) | 63 (42) | 8 (57) | 18 (75) | 12 (40) | 5 (36) | |
| Negative | 126 (54) | 87 (58) | 6 (43) | 6 (25) | 18 (60) | 9 (64) | |
| CD44+/CD24+ | 0.61 | ||||||
| Positive (> 0%) | 14 (6) | 9 (6) | 0 (0) | 3 (12) | 2 (7) | 0 (0) | |
| Negative | 218 (94) | 141 (94) | 14 (100) | 21 (88) | 28 (93) | 14 (100) | |
| CD44-/CD24- | 0.28 | ||||||
| 100% | 78 (28) | 57 (31) | 4 (24) | 5 (18) | 6 (18) | 6 (40) | |
| < 100% | 197 (72) | 125 (69) | 13 (76) | 23 (82) | 27 (82) | 9 (60) | |
Data presented as n (%). SR, steroid receptor. aP values were calculated using Fisher's exact test.