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. Author manuscript; available in PMC: 2009 Jun 26.
Published in final edited form as: Neuroscience. 2008 Apr 11;154(3):1143–1153. doi: 10.1016/j.neuroscience.2008.03.082

Fig. 4.

Fig. 4

Quantitative analysis of neuronal density in hippocampal subfields following systemic administration of KA at 3 different doses to two strains of aged mice. Strain-dependent differences in cell loss in the dentate hilus were observed at all 3 doses of KA. In contrast, strain-dependent differences in cell loss in area CA3 were observed at only the two highest doses (B and C), while cell loss in area CA1 was only observed at a dose of 15 mg/kg (B). No significant differences in the extent of cell loss were observed 7 days following administration of KA, irrespective of dose, in C57BL/6J mice. Data represent the mean ± SEM of eight mice/dose for each strain. *P<0.05.