Fig. 4.

Complex cross-over molecules recovered from sperm DNA. SNPs are indicated by circles, filled for one progenitor haplotype or empty for the other. Each hotspot is indicated on the left, the man of origin of each cross-over is color coded as in Fig. 2A, and the number of cross-overs of each class shown on the right. Cross-overs are aligned with respect to the hotspot centers, with the mean hotspot width of 1.45 kb indicated by shading. Cross-overs marked with an asterisk show haplotype switching extending outside the hotspot.