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. 2008 Jul 14;8:10. doi: 10.1186/1471-2466-8-10

Table 3.

Phospholipid and surfactant protein analyses of lavage specimen

group n (piglets) PL [μg/ml] PPQ LSA [% PL] SP-B/PL [% (w/w)] SP-C/PL [% (w/w)] PC [%] PG [%] PS [%] PI [%]
PPVOLC 5 48.65 ± 7.99 0.08 ± 0.01 47.7 ± 4.4 13.71 ± 3.08 3.06 ± 0.28 73.84 ± 5.57 3.59 ± 1.82 3.97 ± 2.44 6.87 ± 2.37
mon SP-B 4 131.10 ± 59.69 0.33 ± 0.16 62.7 ± 5.3 4.78 ± 2.01** 1.23 ± 0.45** 81.87 ± 1.38* 7.27 ± 2.25* 0.00 ± 0.00** 3.87 ± 1.94
nat SF 4 176.03 ± 68.91** 0.37 ± 0.21* 63.6 ± 6.2* 6.19 ± 1.73** 1.06 ± 0.62*** 81.19 ± 1.43* 8.44 ± 1.10** 0.00 ± 0.00** 3.52 ± 0.79

group n (piglets) PE [%] SPH [%] PUFA [%] Usat FA [%] TL 16:0 [%] Tlfa 20:4 (AA) [%] Tlfa 20:5 (EPA) [%]

PPVOLC 5 7.94 ± 3.63 3.80 ± 1.42 19.94 ± 1.39 40.34 ± 1.41 44.78 ± 1.73 5.54 ± 0.55 0.16 ± 0.03
monSP-B 4 4.99 ± 1.21 2.02 ± 0.85 12.16 ± 3.76** 33.19 ± 3.27** 52.97 ± 3.78** 3.03 ± 0.71** 0.15 ± 0.02
nat SF 4 0.47 ± 0.18 2.11 ± 0.81 11.52 ± 3.09** 35.76 ± 1.78* 50.24 ± 2.17** 2.58 ± 0.82*** 0.29 ± 0.06**

PPQ (phospholipid-to-protein ratio); Phospholipid classes are given as percent (w/w) of all phospholipids. LSA = large surfactant aggregates, given as percent (w/w) of all BALF phospholipids. PC (phosphatidylcholine); PG (phosphatidylglycerol); PS (phosphatidylserine); PI (phosphatidylinositol); PE (phosphatidylethanolamine); SPH (sphingomyelin); Fatty acids were dermined in the BAL total lipid fraction and are given as percent (w/w) of all fatty acids. PUFA (polyunsaturated fatty acids in the total lipid fraction); TL 16:0 (palmitic acid in the total lipid fraction). AA = Arachidonic acid, EPA = Eicospentaenoic acid

* p < 0.05 vs PPVOLC; ** p < 0.01 vs PPVOLC; ***p < 0.001 vs PPVOLC

§ p < 0.05 vs mon SP-B; §§ p < 0.01 vs mon SP-B