Table 4.
λS and sib-sib OR (with 95% CI) for pre-eclampsia.
All races | White | Black | |
Population: pre-eclampsia | 8600 | 6749 | 1736 |
Population: N | 267840 | 220505 | 42861 |
Population risk | 0.032 (0.031–0.033) | 0.031 (0.031–0.031) | 0.041 (0.039–0.043) |
Siblings: sibpairs with both siblings affected | 1070 | 821 | 233 |
Siblings: sibpairs with first sibling affected | 7384 | 5869 | 1400 |
Sibling risk | 0.145 (0.137–0.153) | 0.140 (0.131–0.149) | 0.166 (0.146–0.186) |
λS | 4.5 (4.2–4.8) | 4.5 (4.2–4.8) | 4.1 (3.6–4.6) |
Sib-sib unadjusted OR (95% CI) | 9.2 (8.5–9.9) | 10.0 (9.1–10.9) | 6.7 (5.7–7.9) |
Sib-sib adjusted OR (95% CI)# | 8.1 (7.5–8.8) | 9.0 (8.2–9.8) | 5.8 (4.9–7.0) |
#Adjusted for mother < 20 or > 35 years old, mother < 12 education, Medicaid (index of low SES), no prenatal care, mother BMI < 20 kg/m2, cigarette smoking, insulin-dependent diabetes mellitus, chronic hypertension