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. Author manuscript; available in PMC: 2008 Jul 23.
Published in final edited form as: J Infect Dis. 2006 Jan 30;193(5):721–730. doi: 10.1086/500145

Figure 4.

Figure 4

Distinct and overlapping reactivity to different chondroitin sulfate A (CSA)-binding isolates by serum samples obtained from pregnant women. Binding of IgG to the surface of CS2-, HCS3-, and 3D7-CSA-infected erythrocytes (IEs) was determined using immunofluorescence with flow cytometry. All isolates were tested against the same panel of serum samples obtained from primigravid Malawian women. IgG binding is expressed as a ratio of the fluorescence of IEs to the fluorescence of uninfected erythrocytes. A relative score of 1, denoted by broken lines in the charts, indicates that no significant IgG binding to IEs was detected, compared with uninfected erythrocytes. Correlations are as follows: r = 0.839 and P < .001 for CS2 and 3D7-CSA (top; n = 46); r = 0.837 and P < .001 for CS2 and HCS3 (middle; n = 47); and r = 0.792 and P < .001 for HCS3 and 3D7-CSA (bottom; n = 46).