. Author manuscript; available in PMC: 2008 Jul 23.

Published in final edited form as: J Periodontol. 2002 Nov;73(11):1267–1272. doi: 10.1902/jop.2002.73.11.1267

Table 1.

Kinetic constants for transport of four antimicrobial agents by SCC-25 cells

Agent	K_m (μg/ml)	V_max (ng/min/μg protein)
minocycline	133 ± 14.3	13.4 ± 1.35
doxycycline	507 ± 38.6	5.33 ± 0.62
tetracycline	592 ± 59.8	5.86 ± 0.56
ciprofloxacin	351 ± 12.7	5.11 ± 0.32
ofloxacin	221 ± 20.6	4.24 ± 0.23
moxifloxacin	244 ± 8.43	8.68 ± 0.69

Transport activity was assayed during the rapid initial phase of uptake. The kinetic data was analyzed with the Lineweaver-Burk method to determine the kinetic constants.