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. Author manuscript; available in PMC: 2008 Jul 23.
Published in final edited form as: J Periodontol. 2002 Nov;73(11):1267–1272. doi: 10.1902/jop.2002.73.11.1267

Table 1.

Kinetic constants for transport of four antimicrobial agents by SCC-25 cells

Agent Km (μg/ml) Vmax (ng/min/μg protein)
minocycline 133 ± 14.3 13.4 ± 1.35
doxycycline 507 ± 38.6 5.33 ± 0.62
tetracycline 592 ± 59.8 5.86 ± 0.56
ciprofloxacin 351 ± 12.7 5.11 ± 0.32
ofloxacin 221 ± 20.6 4.24 ± 0.23
moxifloxacin 244 ± 8.43 8.68 ± 0.69

Transport activity was assayed during the rapid initial phase of uptake. The kinetic data was analyzed with the Lineweaver-Burk method to determine the kinetic constants.