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. 2008 Aug;132(2):199–208. doi: 10.1085/jgp.200810024

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© 2008 Hirn et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.jgp.org/misc/terms.shtml). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 3. — Electrophysiological measurements of Na_v1.4 activity in cell-attached patches. (A) Representative traces of cell-attached Na⁺ currents in C57BL/6J (top) and mdx^5cv (bottom) FDB fibers. Of note are the longer inactivation tails in mdx^5cv traces. Currents were elicited with an activation protocol shown on the inset of B. (B) Comparison of average currents (top) and inactivation time constants τ_i (bottom) for the control (open circles, 28 patches) and mdx (filled circles, 33 patches) recordings. Inactivation time constants for potentials below −40 and above 30 mV could not be reliably estimated because of small current amplitude and are not shown. Values are reported as means ± SEM.