Table 1. Risk factors for MI in three case–control studies.

	Study 1		Study 2		Study 3
	Cases (n = 762)	Controls (n = 857)	Cases (n = 579)	Controls (n = 1159)	Cases (n = 475)	Controls (n = 619)
Male, %	60	41	81	42	61	62
Age at enrollment, median (range)	62 (29–87)	65 (24–100)	66(28–88)	58 (45–97)	60 (32–86)	58 (37–88)
Age at MI, median (range)	52 (27–82)	NA	57 (21–70)	NA	53 (29–77) †	NA
Smoking, %	66	45	68	40	73	54
Diabetes, %	20	0‡	25	0‡	38	10
Dyslipidemia§, %	84	53	84	61	95	56
Hypertension||, %	61	32	66	33	96	78
BMI (kg/m2), mean±SD	28±5	26±5	28±5	26±5	31±6	30±7

^†Data available for 254 cases.

^‡Individuals with diabetes were excluded from control group.

^§Dyslipidemia was defined in Study 1 and Study 2 to be self-reported history of a physician diagnosis of dyslipidemia or the use of lipid lowering prescription medication(s) and defined in Study 3 to be the use of lipid lowering prescription medication(s), LDL cholesterol >129 mg/dL, triglycerides >149 mg/dL or HDL cholesterol <45 mg/dL .

^||Hypertension was defined in Study 1 and Study 2 to be a self–reported history of a physician diagnosis of hypertension or use of antihypertensive prescription medication(s) and defined in Study 3 to be the use of antihypertensive prescription medication(s), systolic blood pressure >160 mmHg, or diastolic blood pressure >90 mmHg.

NA; not applicable.