Table 2. Blood Chemistry and Tissue Weight of ob/ob and ob/ob/Fsp27 −/− mice.
ob/ob | ob/ob/Fsp27 −/− | ||||
N | Mean±SEM | N | Mean±SEM | P | |
NEFA (mEq/l) (Fed) | 8 | 3.906±0.383 | 8 | 3.617±0.212 | 0.2946 |
NEFA (mEq/l) (Fast) | 8 | 4.582±0.686 | 8 | 3.873±0.382 | 0.01148 * |
TG (mg/l) (Fed) | 8 | 0.3185±0.0142 | 8 | 0.3682±0.0216 | <0.0001 *** |
TG (mg/l) (Fast) | 8 | 0.3584±0.0222 | 8 | 0.4256±0.0232 | 0.0028 ** |
Cholesterol (mmol/l) (Fed) | 8 | 5.805±0.014 | 8 | 6.518±0.013 | 0.016 * |
Cholesterol (mmol/l) (Fast) | 8 | 5.517±0.020 | 8 | 6.147±0.007 | 0.04748 * |
Insulin (ng/ml) (Fed) | 8 | 7.986±0.162 | 8 | 6.290±0.209 | <0.0001 *** |
Insulin (ng/ml) (Fast) | 8 | 7.426±0.320 | 8 | 6.011±0.133 | <0.0001 *** |
Glucose (mmol/l) (Fed) | 12 | 17.24 ± 1.129 | 12 | 16.76± 1.210 | 0.3226 |
Glucose (mmol/l) (Fast) | 12 | 11.90 ± 1.369 | 12 | 11.37± 0.884 | 0.2692 |
Gonadal Fat Pad | 10 | 0.061 ± 0.007 | 10 | 0.004 ± 0.002 | <0.0001 *** |
BAT | 10 | 0.061 ± 0.007 | 10 | 0.004 ± 0.002 | <0.0001 *** |
Liver | 10 | 0.102 ± 0.009 | 10 | 0.009 ± 0.002 | <0.0001 *** |
All values are means ± s.e.m. Statistical analysis was done with two-tailed unpaired student t-test. N represents number of mice used.
P<0.05,
P<0.01,
P<0.001