Figure 5.
Reduction of MTT (3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide) in SMCs is suppressed by increasing concentrations of 7-ketocholesterol (7-KC) and by 100 μM fluvastatin (a) or 100 μM simvastatin (b). Results shown as mean absorbance±s.e.mean, n=9–10, except for 100 μM n=3. Significance of the effects of 7-ketocholesterol, statin and their interaction in a factorial ANOVA is shown.