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. 2008 May 14;10(3):R57. doi: 10.1186/ar2426

Table 1.

Regression analysis of membrane n-3 LCPUFA content versus lymphocyte subpopulationa numbers and cytokine production

EPA DHA n-3 LCPUFAc

rb p valueb r p value r p value
CD3+ -0.32 0.07 -0.06 0.74 -0.20 0.27
CD4+ -0.34 0.06 -0.04 0.84 -0.19 0.28
CD8+ -0.17 0.36 -0.07 0.70 -0.12 0.50
CD4+:CD8+ 0.14 0.45 0.01 0.94 0.06 0.73
CD16+CD56+ -0.39d 0.025 -0.37 0.033 -0.38 0.029
CD19+ -0.13 0.47 -0.11 0.56 -0.12 0.50
IFNγ 0.17 0.43 0.13 0.56 0.16 0.50
IL-2 0.23 0.30 0.23 0.30 0.26 0.24
LT 0.43 0.046 0.18 0.44 0.27 0.22
Lymphocytes -0.45 0.009 -0.21 0.25 -0.28 0.11
Neutrophils -0.24 0.18 -0.31 0.065 -0.31 0.078
Monocytes 0.06 0.80 0.41 0.11 0.28 0.27
Total leukocytes -0.33 0.06 -0.32 0.07 -0.34 0.06

aCD3+, all circulating T cells; CD4+, all T helper cells; CD8+, all cytotoxic T cells; CD19+, all B lymphocytes; CD16+CD56+, all NK cells; IFNγ, interferon-gamma; IL-2, interleukin 2; LT, lymphotoxin. bThe correlation coefficient r value; the p value shows the significance (p < 0.05) (ANOVA) of the obtained r value. cn-3 LCPUFA refers to the sum of docosapentaenoic acid (DPA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). dBoldfaced text shows results with r value of p < 0.05.