Table 3.
Group | CRP reduction at day 43 versus baseline | ACR response at day 43 | ||
<20% | 20% to <50% | 50% or more | ||
10 mg/kg ACZ885 | <20% | 4 | 0 | 0 |
20 to <50% | 0 | 1 | 1 | |
50% or more | 8 | 2 | 2 | |
Placebo | <20% | 9 | 1 | 0 |
20 – <50% | 2 | 0 | 0 | |
50% or more | 3 | 0 | 0 |
Relationship between C-reactive protein (CRP) reduction and American College of Rheumatology (ACR) response at day 43 for patients in the 10 mg/kg group and patients receiving placebo. Note that two subjects are excluded from the 10 mg/kg ACZ885 because of missing data.