Table 2. Endogenous retinoids in mouse tissues.
| Serum/Tissue | RE (nmol/g) | ROL (nmol/g) | RAL (pmol/g) |
|---|---|---|---|
| &serum# | 0.22 ± 0.02 (69) | 0.81± 0.04 (70) | 32.2 ± 6.2 (6) |
| &liver | 562.6 ± 75.9 (55) | 9.6 ± 0.9 (60) | 160.9 ± 14.3 (26) |
| &kidney | 1.8 ± 0.2 (37) | 0.60 ± 0.04 (37) | 187.3 ± 31.2 (12) |
| &adipose (white) | 0.59 ± 0.09 (29) | 0.63 ± 0.03 (37) | 63.5± 5.2 (12) |
| &adipose (brown) | 0.99 ± 0.21 (5) | 0.64 ± 0.21 (5) | --- |
| &muscle | 0.25 ± 0.03 (31) | 0.15 ± 0.02 (38) | --- |
| &spleen | 1.2 ± 0.1 (26) | 0.60 ± 0.06 (26) | --- |
| &testis | 0.31 ± 0.02 (27) | 0.08 ± 0.01 (27) | 90.7 ± 10.1 (12) |
| &skin | 0.22 ± 0.02 (5) | 0.32 ± 0.01 (5) | --- |
| **brain | 0.84 ± 0.16 (19) | 0.68 ± 0.23 (19) | --- |
| **hippocampus | 0.70 ± 0.05 (27) | 0.30 ± 0.03 (27) | --- |
| **cortex | 0.35 ± 0.04 (18) | 0.08 ± 0.01 (18) | --- |
| **olfactory bulb | 0.63 ± 0.03 (4) | 0.20 ± 0.02 (4) | --- |
| **thalamus | 0.47 ± 0.06 (4) | 0.20 ± 0.04 (4) | --- |
| **cerebellum | 0.73 ± 0.10 (8) | 0.42 ± 0.08 (8) | --- |
| **striatum | 0.41 ± 0.08 (4) | 0.21 ± 0.05 (4) | --- |
&
Data were obtained from 2 to 4 month-old male SV129 mice fed and bred from dams fed an AIN93G diet with 4 IU vitamin A/g.
**
Data were obtained from 2 to 4-month-old male C57BL/6 mice fed an AIN93M with 4 IU vitamin A/g from weaning and bred from dams fed a stock diet (>30 IU vitamin A/g). Values are means ± SEM. The numbers in parentheses indicate the number of samples assayed. Each sample was obtained from an individual mouse.
---, not measured.
#
serum RE and ROL values are expressed in nmol/mL and RAL values are expressed in pmol/mL.