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Amygdala volumes as a function of age tertiles. The bipolar and control samples were divided into the low (age 18-25), middle (age 26-34), and upper thirds (age 36-49) of their respective age distributions. Amygdala volume of bipolar patients in the oldest age cohort is significantly decreased relative to healthy controls in the (a) left and (b) right hemispheres, * P < .05.
