Table 2. Given number of chambers C and counts H 1 and H 2 of the positive chambers in a digital array for the target gene and the reference gene, respectively, list of formulas needed to analyze copy number variation.
, |
, |
pˆ 1,Low = pˆ 1−1.96S 1, pˆ 1,High = pˆ 1+1.96S 1 |
pˆ 2,Low = pˆ 2−1.96S 2, pˆ 2,High = pˆ 2+1.96S 2 |
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, , |
, |
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See the details in the paper for assumptions made so that these equations are close approximations to actual values.