Figure 6. Network of hydrogen bonds in the necks of BadA, YadA and Hia.

Intramolecular H-bonds are marked as blue lines, intermolecular ones as red lines. Residues involved in intermolecular H-bonds are yellow, residues involved in intramolecular H-bonds are blue, highly conserved hydrophobic core residues that also contribute to the H-bond network are green. Note that all H-bonds involve atoms of the main chains, which explains the low conservation of sidechains between neck sequences. * marks the insertion in the Hia sequence (see text).