Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Patient demographics (mean ± SD) and CYP2D6 genotype/phenotype status
| Age (years) | Weight (kg) | CYP2D6 genotype | |
|---|---|---|---|
| IMs (n = 6) | 39.8 ± 6.1 | 72.3 ± 8.0 | *10/*10 (n = 5) |
| *36/*41 (n = 1) | |||
| EMs (n = 13) | 40.6 ± 13.2 | 73.7 ± 12.6 | *1/*2 (n = 1) |
| *1/*10 (n = 9) | |||
| *1/*41 (n = 1) | |||
| *2/*10 (n = 1) | |||
| *2/*5 (n = 1) | |||
| NA (n = 1) | 42 | 49 | – |
| All (n = 20) | 40.5 ± 11.0 | 72.1 ± 12.1 | – |
EMs, extensive metabolizers; IMs, intermediate metabolizers; NA, CYP2D6 status unknown.
