Table 2.

Association of non-antidiabetic drugs with hypoglycaemia in the French pharmacovigilance database, in reports including or not including antidiabetic agents

	All reports	Hypoglycaemia	ROR*	95% CI†
Reports including ADAs	3 469	299	–	–	–
ARB‡	275	11	0.4	0.2	0.8
ACEI§	336	31	1	0.7	2
Atenolol	154	7	0.5	0.2	1
DHP¶	248	12	0.5	0.3	0.9
Frusemide	666	48	0.8	0.6	1
Cibenzoline	13	4	5	2	16
Reports not including ADAs	171 126	508	–	–	–
ARBs‡	2 234	10	2	0.8	3
ACEIs§	2 366	8	1	0.6	2
Atenolol	1 806	12	2	1	4
DHP¶	2 122	10	2	1	3
Frusemide	7 173	45	2.2	2	3
Cibenzoline	167	53	174	124	244

^*ROR, reporting odds ratio of association of selected drug with hypoglycaemia (see Table 2).

^†95% CI, lower and upper limits of 95% confidence interval for OR.

^‡ARBs, angiotensin receptor blockers (losartan or irbesartan).

^§ACEIs, angiotensin converting enzyme inhibitor (enalapril or captopril).

^¶DHP, dihydropyridines (nifedipine, nicardipine, nitrendipine, nimodipine).