Table 4.

Univariate and multivariate relative risks for recurrence of cardiovascular disease in the different cohorts

Outcome predictor	Univariate		Multivariate§
	RR	95% CI	RR	95% CI
Aspirin-alone cohort
Adherence to aspirin (%)
<80	1.00		1.00
80–100	1.14	1.04, 1.24	1.08	0.97, 1.21†
Statin-alone cohort
Adherence to statin (%)
<80	1.00		1.00
80–100	0.83	0.61, 1.12	0.66	0.47, 0.91*
Combination cohort
Adherence to both (%)
Both <80%	1.00		1.00
Statin ≥80% and aspirin <80%	0.67*	0.52, 0.86	0.64	0.49, 0.82**
Statin <80% and aspirin ≥80%	0.93	0.74, 1.18	0.91	0.72, 1.15
Both ≥80%	0.82*	0.68, 0.99	0.69	0.56, 0.84**

^§Adjusted for age, gender, social deprivation, calendar year, diabetes mellitus, cardiovascular drug use during follow-up and number of cardiovascular prescriptions.

^†Also adjusted for interaction between aspirin adherence and nonsteroidal anti-inflammatory drug use.

^*P < 0.05;

^**P < 0.01.