Table 1.
Comparison of Fos-IR Nuclei per Region of Interest Following Injection of GR73632 or Saline. Data is presented (mean ± SEM) for each group and each region of interest. Significance level was determined by two-tailed Student’s T-test between groups, and was considered statistically significant when p ≤ 0.05. Significant differences between GR73632 and saline injected groups (N=6 per group) were found in the NTS, the DMNX, and the ENS.
Region of Interest | GR73632 | Saline | Significance level |
---|---|---|---|
PFC | 116.8 ± 27.9 | 173 ± 26.4 | 0.25 |
NTS | 20.5 ± 2.8 | 8.1 ± 2.9 | 0.004 |
AP | 4.8 ± 1.7 | 2.0 ± 1.2 | 0.178 |
DMNX | 4.9 ± 1.2 | 1.8 ± 0.7 | 0.047 |
ENS | 11.8 ± 3.2 | 5.2 ± 2.6 | 0.05 |
Abbreviations: AP – area postrema; DMNX – dorsal motor nucleus of the vagus nerve; ENS – enteric nervous system; NTS – nucleus of the solitary tract; PFC – prefrontal cortex.