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Equilibrium dissociation constants (KD values) for complexes between NORE1A and Ras and Rap mutants
| NORE1A wt | NORE1A K302D | |||
|---|---|---|---|---|
| KD (μM) | KD (mut)/KD (wt) | KD (μM) | KD (mut)/KD (wt) | |
| Ras | ||||
| wt | 0.08 | — | 0.71 | 9 |
| D30E/E31K | 1.23 | 15 | 0.77 | 0.1 |
| Y64A | 7.5 | 94 | — | — |
| Rap1A | ||||
| wt | 1.3 | — | 0.7 | 0.55 |
| E30D/K31E | 0.17 | 0.13 | 1.1 | 6.6 |
