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Presynaptic inhibition of fast synaptic transmission in an S neuron in the submucous plexus of guinea pig ileum. a Left A fast EPSP was evoked by a single stimulus to an interganglionic fibre tract. Right Exposure to adenosine for 5 min suppressed the fast EPSP. b Left Depolarization to pressure application of DMPP (1 μM). Right During blockade of the fast EPSP, the depolarization to DMPP was unchanged in the presence of adenosine. Adapted from [114]. Copyright © Gastroenterology
