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. 2008 Jun 12;27(13):1852–1862. doi: 10.1038/emboj.2008.118

Figure 5.

Figure 5

The B-Myb M14 mutant delays mitosis and causes aneuploidy. (A) Increase in mitotic index in the M14-reexpressing cells and the B-Myb-deficient cells. The mitotic index of MEFs from the above experiments is shown. n=235–589. *P<0.05. (B) The histogram shows the percentage of mitotic cells, relative to controls, at each stage in mitosis. Values are mean+s.e.m. *P<0.05; **P<0.001. n=300. (C) Multiploidy in M14-reexpressing cells and the B-Myb-deficient cells. The indicated cell types were analysed by FACS (n=3). (D) Abnormal numbers of centrosomes in M14-reexpressing cells and the B-Myb-deficient cells. The number of centrosomes was examined by immunostaining with anti-γ-tubulin. *P<0.05. n=120.