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. Author manuscript; available in PMC: 2008 Oct 1.
Published in final edited form as: Glia. 2007 Oct;55(13):1385–1396. doi: 10.1002/glia.20544

Figure 4. IL-4 and IL-13 enhance IFN-γ -induced IDO expression but reduce WRS expression in mouse microglia.

Figure 4

Microglia were stimulated with cytokines for 24 hrs and total RNA was analyzed for IDO (A, B) and WRS (C, D) expression by real time RT-PCR. Data are representative of six independent experiments with IL-4 and seven independent experiments with IL-13 done in triplicate. IDO expression in IFN-γ stimulated cells was significantly increased by treatment with IL-4 or IL-13, whereas IFN-γ stimulated WRS expression significantly reduced by IL-4 or IL-13.