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Analysis of pituitary phenotype. Pituitary glands from 7-month-old wild-type and FSH-R mutant mice were fixed in OCT compound, and 10-μm cryostatic sections were prepared. The expression of the indicated gene was analyzed. Note the increased signal for FSH and TSH in mutant mice. GH, growth hormone; PRL, prolactin; POMC, proopiomelanocortin.
