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Time course of (a) cell death (PI negative cells), (b) blebbing, and (c) nuclear fragmentation of wild-type, caspase-1−/−, and caspase-3−/− hepatocytes after coculture with NIH 3T3 fibroblasts (○) or FasL-expressing NIH 3T3 fibroblasts with (▵) or without (□) caspase inhibitor z-VAD.fmk (10 μM).
