Figure 1.

The appearance of clonal cultures of chemically transformed, highly aneuploid (A and B) and little aneuploid or near-diploid (C and D) CHE cells and of clones of flat CHE cells with the normal modal chromosome number 22 (E and F). The highly aneuploid clone B6-4 (A) and the near-diploid clone D3-10 (C) consist of spindle-shaped cells. The highly aneuploid clone M11-1 (B) and the little aneuploid clone M8-11 (D) consist of polygonal cells. The flat clone B6-5 (E) consists of spindle-shaped cells, and the flat clone D3-8 (F) consists of polygonal cells.