Skip to main content
. 2008 May 1;149(8):3881–3889. doi: 10.1210/en.2008-0288

Figure 3.

Figure 3

Receptor-mediated regulation of VEGF release. A, Concurrent exposure of HTERα cells to 17β-estradiol and MPP (ERα antagonist) at both the 1 and 10 μg Dox dose completely blocked 17β-estradiol mediated increase in VEGF. *, P < 0.05). Bars represent mean ± sem of a single representative experiment, with n = 6 for each treatment condition. B, RT-PCR indicated that the VEGF primers detected the appropriate size band (342 bp) for the VEGF gene, but there was no variation in the expression of VEGF mRNA as a result of 17β-estradiol treatment or increased Dox doses. Cyclophilin was also amplified from the same samples and used here to indicate that equal amount of RNA was amplified in each case.